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Restriction Fragment Length Polymorphisms (RFLPs) result in differing length DNA fragments between samples due to varying length introns.
Why is RFLP analysis such a useful tool in biotechnology today?
It can amplify segments of genes such as those involved in Huntington’s disease.
It can be utilized in forensic science to determine the genetic frequency of alleles in a population using Hardy-Weinberg equilibrium.
It can determine phenotypic ratios expected in offspring based on presence or absence of dominant or recessive alleles in the P generation.
It can be used to accurately differentiate DNA samples between different sources, utilized in evolutionary analysis, forensics, paternity testing, and for finding genes linked to diseases.