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Applications of RFLP Analysis

APBIO-LJ34NG

Restriction Fragment Length Polymorphisms (RFLPs) result in differing length DNA fragments between samples due to varying length introns.

Why is RFLP analysis such a useful tool in biotechnology today?

A

It can amplify segments of genes such as those involved in Huntington’s disease.

B

It can be utilized in forensic science to determine the genetic frequency of alleles in a population using Hardy-Weinberg equilibrium.

C

It can determine phenotypic ratios expected in offspring based on presence or absence of dominant or recessive alleles in the P generation.

D

It can be used to accurately differentiate DNA samples between different sources, utilized in evolutionary analysis, forensics, paternity testing, and for finding genes linked to diseases.