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Autoimmune Diseases

APBIO-XXEE2E

Autoimmune diseases arise from the inadvertent recognition of self-antigens by one's own immune system.

Which of the following are likely causes of self-recognition?

A

Failure of one's immune system to eliminate self-recognizing cells.

B

Chronic exposure to allergens such as pollen.

C

Somatic mutations that lead to the creation of self-recognizing cells.

D

Uncontrolled proliferation of lymphocytes, as in the case of leukemia, which leads to T-cells with the ability to recognize self.