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Effects of Mutations


Sickle cell anemia is caused by the mutation of a single base pair in the gene for hemoglobin. This mutation results in hemoglobin molecules that form long chains in low-oxygen settings and stretch the blood cells into their characteristic sickle shape.

Which of the following would result if a different base pair in the sickle cell hemoglobin gene were to become mutated?


The effects of sickle cell would be increased.


The effects of sickle cell would be reduced.


The new mutation would increase resistance to malaria.


It is impossible to predict what the effect would be without knowing more about the mutation.