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Effects of Mutations

APBIO-UN4KEA

Sickle cell anemia is caused by the mutation of a single base pair in the gene for hemoglobin. This mutation results in hemoglobin molecules that form long chains in low-oxygen settings and stretch the blood cells into their characteristic sickle shape.

Which of the following would result if a different base pair in the sickle cell hemoglobin gene were to become mutated?

A

The effects of sickle cell would be increased.

B

The effects of sickle cell would be reduced.

C

The new mutation would increase resistance to malaria.

D

It is impossible to predict what the effect would be without knowing more about the mutation.