There are four known steps in embryonic stem cell development. Embryonic stem cells are undifferentiated mitotic products within a blastocyst. These cells are described as pluripotent, capable of becoming any cell type for a specific organism, given the right molecular directives for selective gene expression. The stages are defined below, however, are not in the correct order in cell development.
I. Morphogenesis: the formation of the correct shape and placement of cells in tissues within organs of an organism.
II. Growth: the size increase of a cell as a result of cell division and cell enlargement.
III. Determination: established fate of a cell.
IV. Differentiation: the active transformation of developing cells into specialized and committed cell types.
Which of the following is the BEST sequence of events in embryonic stem cell development?