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Biochemistry

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Essentials of Peptide Primary Structures

BIOCHM-WYMMSJ

Peptide primary structures are based on amide bonds.

Four scenarios of amide bond replacement are presented below, identify the altered properties or characteristics.

Scenario 1: Instead of an amide bond, an ester bond would

of the primary structure.

Scenario 2: Instead of an amide bond, a ketone bond would

of the primary structure.

Scenario 3: Instead of an amide bond, an imine bond would

of the primary structure.

Scenario 4: Instead of an amide bond, a thioester bond would

of the primary structure.