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Biochemistry

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Moderate

Formation of O-linked Glycoproteins

BIOCHM-CL11GG

Glycoproteins are a class of proteins that have oligosaccharides (short chains of carbohydrates) covalently attached to the protein. Typically membrane-bound, glycoproteins are sometimes called glycopeptides.

In O-linked glycoproteins,

A

an oligosaccharide forms an O-glycosidic bond with an Asn residue of the protein.

B

an oligosaccharide forms an O-glycosidic bond between a side chain atom of the protein and an –OH group on the oligosaccharide.

C

an oligosaccharide forms an O-glycosidic bond with the α-carbon on a residue of the protein.

D

an oligosaccharide forms an O-glycosidic bond involving the anomeric carbon of the oligosaccharide.