Biochemistry

Free Version

Upgrade subject to access all content

Moderate

Regulation of Cholesterol Synthesis

BIOCHM-A0GSLV

Which of the following statements about the regulation of cholesterol synthesis is NOT correct?

A

Cholesterol acquired in the diet has essentially no effect on the synthesis of cholesterol in the liver.

B

Failure to regulate cholesterol synthesis predisposes humans to atherosclerosis.

C

High intracellular cholesterol stimulates formation of cholesteryl esters.

D

Insulin stimulates HMG-CoA reductase.

E

Some metabolite or derivative of cholesterol inhibits HMG-CoA reductase.