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Removal of "Old" Serum Glycoproteins


Serum glycoproteins play many roles in an organism, but they eventually need to be removed from circulation.

Newly-synthesized glycoproteins all contain oligosaccharide chains that end with


Glycoproteins that have grown too old lose that tag, and are recognized by the

receptor in the


Upon binding, the glycoproteins are then internalized and destroyed.