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Cellular and Molecular Biology

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Alternative Splicing: Proteomic Diversity

CELLS-JIULMU

Alternative splicing is the ability of a a single gene to produce diverse proteins. It entails the use of transcribed pre-mRNA to be spliced into various exon combinations.

Alternative splicing is carried out by a

, a huge molecular structure comprised of five

and a large group of other proteins that together recognize splice sites in the pre-mRNA and catalyze the splicing reaction.

Alternative splicing leads to enhanced diversity in the

relative to the

.