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Cellular and Molecular Biology

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B Cell Activation: Events After Antigen-Binding

CELLS-7GNZPY

After membrane-bound Ig (mIg), expressed on the surface of a B cell, binds to its antigen, several events take place to activate that B cell.

Which of the following does NOT occur as a result of this antigen-binding?

A

The antigen is internalized by receptor-mediated endocytosis.

B

A signal cascade is initiated that results in the upregulation of MHC II.

C

A signal cascade is initiated that results in the expression of membrane receptors for cytokines, including IL-2.

D

The antigen is processed into peptides for presentation to T helper cells.