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Cellular and Molecular Biology

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Moderate

Cancer Cells and Initiation of Metastasis I

CELLS-YRIFJW

In order for a cancer cell to metastasize and leave the primary tumor, it has to become invasive and enter the circulation. Therefore the cell has to become less adhesive to neighboring cells and more migratory.

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For certain types of stomach and breast cancers, E-cadherin, a protein found associated with the cell junctional complex

, is found to be

in expression.