Cellular and Molecular Biology

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Cross-Presentation of Antigen

CELLS-YW4GIS

Antigen presenting cells display small fragments of antigen on their surface for T-cell recognition.

Which of following BEST defines the immunological term 'cross-presentation'?

A

Extracellular antigens are internalized and redirected from the exogenous to the endogenous pathway, where they are presented on MHC II molecules.

B

Intracellular antigens are redirected from the endogenous pathway to the exogenous pathway, where they are presented on MHC II molecules.

C

Extracellular antigens are internalized and redirected from the exogenous to the endogenous pathway, where they are presented on MHC I molecules.

D

Intracellular antigens are redirected from the endogenous pathway to the exogenous pathway, where they are presented on MHC I molecules.