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Cellular and Molecular Biology

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Detection of Gene Amplification in Cancer Cells

CELLS-5EOSYH

Cancer can develop from alterations in tumor suppressor genes and oncogenes in the genome. Some of these structural changes include gene amplifications, gene deletions, chromosomal translocations, and intrachromosomal inversions.

Which of the following methods would be able to detect gene amplification events?

Select ALL that apply.

A

Southern blot.

B

QPCR.

C

CHIP.

D

FISH.