Cellular and Molecular Biology

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Epigenetics and Tumorigenesis


Changes in DNA methylation are recognized as major drivers of tumorigenesis.

Please choose the BEST answers from the dropdown prompts below.

For example, 25% of acute myeloid leukemias arise from DNA hypomethylation in gene promoters. This is

in DNA methylation at

which leads to

in gene expression.

Conversely, a high proportion of colorectal cancers have DNA hypermethylation, which is

in DNA methylation that generally leads to

in gene expression.