Cellular and Molecular Biology

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Epithelium: Connective Tissue Protein Tethers

CELLS-B4NOJL

Epithelial tissue is connected to the underlying connective tissue via special protein tethers or connections.

The micrograph below shows normal skin and skin from an individual with a disease that disrupts the basal lamina. The arrow points to the basal lamina in the normal tissue. The two arrows indicate the separation of tissue in the diseased state.

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Which ONE of the following proteins is NOT likely to be mutated in the diseased tissue?

A

Laminin.

B

Type IV collagen.

C

Type VII collagen.

D

Dynein.

E

Dystonin.