Cellular and Molecular Biology

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Histocompatibility and HLA Haplotypes

CELLS-BT71HL

MHC genes are inherited as a single genetic unit, known as a haplotype. In a typical pattern of human inheritance, each parent will pass on one unique haplotype to their offspring.

Assuming a lack of recombination, what is the likelihood that two siblings will be histocompatible (contain the same haplotypes)?

A

25%

B

50%

C

75%

D

100%