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Cellular and Molecular Biology

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Inducing Cell Death in Cancer Cells

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The goal of chemotherapeutics in the treatment of cancers is to provide a cytotoxic environment that hopefully will be sufficient to kill the cancer cells.

These agents target different aspects of cell function, such as DNA replication, generally to prevent the process from occurring within the cell. Chemotherapy is a non-selective strategy that will kill cancer cells, but also normal cells that are undergoing replication.

Cytotoxic-based chemotherapy is designed to stimulate which cellular process in order to induce cell death in cancer cells?

A

Autophagy.

B

Apoptosis via the Extrinsic Pathway.

C

Apoptosis via the Intrinsic Pathway.

D

Necrosis.