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Cellular and Molecular Biology

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Structure and Function of Nucleosomes

CELLS-TKLRMW

Nucleosomes are composed of eight histone protein cores. Histones are alkaline proteins that exist in a wide range of variants. Nucleosomes contain two sets of histones H2A, H2B, H3 and H4, thus forming an octamer. Nucleosomes are an integral part of chromatin.

As such, nucleosomes are part of which of the following?

Select ALL that apply.

A

Gene regulatory apparatus.

B

Post-translational modification apparatus.

C

Ribosomal apparatus.

D

DNA packaging apparatus.

E

Chromosomal centromeres.