Many proteins are modified following translation.
Sumoylation is a post-translational modification process similar to
in regard to the type of enzymatic reactions.
However, rather than
, sumoylation involves addition of
Sumoylation is involved with many processes involving proteins such as the subcellular localization of proteins, protein partnering, and transactivation functions of transcription factors.
The majority of proteins that are sumoylated are
proteins. Sumoylated proteins are covalently attached to
residues in proteins.