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Genetics and Genomics

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Determination of a DNA Sequence from Polypeptides

GENES-796CEP

When examining a eukaryotic protein, you find five mutants in the same region of the polypetide. The mutant sequences are as follows:

MET GLY TRP ARG MET

THR GLY TRP ARG VAL

MET GLY TRP MET VAL

MET STOP

MET GLY SER ARG VAL

From these mutants, determine what the wild-type DNA sequence must be. Be sure to write the DNA sequence with no spaces and in the 5' to 3' direction.