Genetics and Genomics

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Determining Potential Mode of Inheritance from Pedigrees

GENES-GEYM0N

Created for Albert.io. Copyright 2016. All rights reserved.

Tracing of inheritance patterns of certain human diseases can be accomplished by studying pedigrees.

Boxes represent males, circles represent females, open figures represent non-afflicted individuals, and filled figures indicated afflicted individuals. Horizontal lines between individuals indicate marriages with the resulting offspring connected below them.

In this pedigree there is an afflicted person in Generation I and another afflicted person in Generation IV. There is a consanguineous marriage (between relatives) among Generation III individuals.

Based on the information provided in the pedigree, what is the most likely answer regarding the inheritance of this disease?

A

It is recessive.

B

It is dominant.

C

It is sex-linked.

D

It only affects females.