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Genetics and Genomics

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Functional Genomics: DNA Microarrays

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DNA microarrays are used to analyze gene expression levels of large numbers of genes simultaneously. A DNA microchip has many different microscopic DNA spots attached to a surface, such as plastic, glass, or silicon. The chip is probed using the test sample to determine if it contains the specific sequence of interest.

GeneChips used in DNA microarray analysis. The match is used to show size comparison. Wikipedia, n.d. Web. 30 July 2016.

The principle underlying this technique is that complementary DNA strands will specifically pair with each other by forming

between complementary

.