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Genetics and Genomics

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Moderate

Genotype and Allele Frequency Calculation

GENES-$GFBGA

Assume that two alleles (A1 and A2) are segregating in a diploid, sexually reproducing population. In a randomly selected sample from this population, the following genotypes (and numbers) were observed: A1A1 (n = 165), A1A2 (n = 260), and A2A2 (n = 75).

Based on this sample, calculate the frequencies of the three genotypes and the two alleles.