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Genetics and Genomics

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X Chromosome Inactivation in Mammals

GENES-HJ8EJU

In the late 1940s, Murray Barr reported a dark staining area in the nucleus of cells from female cats. In the early 1960s, Mary Lyon suggested that these dark-staining areas in cells from female mammals were inactivated X chromosomes.

These dark-staining structures in female mammalian cells became known as

A

Little Lyons.

B

Barr flies.

C

Barr bodies.

D

Sand barrs .