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Genetics and Genomics

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X-Inactivation Phenomenon in XX-XY Sex Determining Systems

GENES-JFNXRS

In species with XX -XY sex determinations systems, cells in females all contain two copies of the X chromosome (as well as two copies of all of the genes on the X chromosome) while cells in males contain only one copy of the X chromosome.

A gene on the X chromosome known as Xist (X-inactivation-specific transcript) produces an RNA transcript that coats and inactivates one of the X chromosomes in every female cell.

Which of the following terms BEST describes this scenario?

A

Genetic anticipation.

B

Sex determination.

C

Gene dosage compensation.

D

Dominance.

E

Epistasis.