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Neuroscience

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Driving Force for Movement of Ions

NEURO-FAV6$F

The driving force for movement of a given ion across a neuronal membrane is the difference between the membrane potential and the equilibrium potential of that ion is given by: ${ V }_{ m } - { E }_{ ion }$.

In most mammalian neurons, both the resting membrane potential and the equilibrium potential of chloride ion is around -65mV.

This means that

A

there is no net leakage of chloride ions inward or outward at the resting membrane potential.

B

there is no ${ Cl }^{ - }$ channel on the membrane.

C

if we suddenly increased the number of open ${ Cl }^{ - }$ channels in the membrane, there will be an outward chloride current and a depolarization of ${ V }_{ m }$.

D

depolarization of the membrane potential decreases the driving force for chloride ions.