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Neuroscience

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The MC4 Receptor and Eating Behavior

NEURO-UR1UVC

MC4 protein (human melanocortin receptor), a G protein-coupled receptor binds $\alpha$-melanocyte stimulating hormone ($\alpha$-MSH). The MC4 receptors on hypothalamic neurons have their function blocked by AgRP (agouti-related peptide).

Activation of the MC4 receptor results in which of the following?

A

Reduces eating behavior.

B

Promotes behavior which results in obesity.

C

Stimulates the release of NPY (Neuropeptide Y).

D

Stimulates the release of CART (cocaine-and amphetamine-regulated-transcript).