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Organic Chemistry 2

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Carbonyl Compound Acidity

ORGO2-WIAYBV

Deprotonation of hydrogens alpha to carbonyl groups is an important first step in numerous carbon-carbon bond forming processes, most notably the aldol and Claisen condensations, and various alkylation reactions.

Which of the compounds below is the MOST acidic?

A

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B

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C

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D

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E

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