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Organic Chemistry 2

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Ketone Transformation with Alpha Carbonyl Substitution V

ORGO2-W1JLPU

What is the likely product at the end of the following reaction sequence?

A key carbon-carbon bond-forming step in this reaction involves coupling the enol derived from the starting ketone with an activated derivative of the amide, N,N-dimethylformamide. The $^1$H NMR spectrum for the product is depicted.

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A

Created for Albert.io. Copyright 2016. All rights reserved.

B

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C

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D

Created for Albert.io. Copyright 2016. All rights reserved.