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In Act 4, scene 1, Iago says, "Work on, my medicine, work!"
What is his medicine?
The herbs he is giving Othello for his epilepsy.
The scheming he is doing with Roderigo.
The medicine he is taking to prevent him from exhibiting emotion.
The "poison" with which he is filling Othello's head to make him jealous.
The words with which he is wooing Desdemona.