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Rue’s death is MOST significant to the story because
Rue was the youngest tribute.
Rue reminded Katniss so much of Prim.
it enables Katniss to turn her rage toward the Capitol as well as toward her fellow tributes.
it ends the only alliance that Katniss had in the games and leaves her on her own.
Rue was able to find medicine and other foods that Katniss needs to survive.