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All organisms rely on homeostasis to maintain a stable internal environment for normal physiological function. Insulin is a protein hormone essential in the regulation of blood glucose, and an absence of insulin causes the medical condition known as diabetes. The mechanism of insulin action is illustrated below:

"Insulin Action."Wikipedia Commons. N.p., n.d. Web.

Which of the following BEST explains how insulin is involved in maintaining homeostasis?


Insulin combines with its membrane receptor and initiates a response in the target cell. The response includes the conversion of glucose into glycogen inside the cell, and this demonstrates positive feedback.


The glucose transporter protein triggers the transport of insulin into the cell, and signal transduction leads to the conversion of glucose into glycogen, fatty acids, and pyruvate.


Insulin and glucose work simultaneously to produce glycogen, fatty acids, and pyruvate via negative feedback.


Insulin binds to cell receptors, which causes a drop in blood sugar when glucose moves into the target cell and is converted to glycogen. This demonstrates negative feedback.

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