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A doctor wishes to compare pain relief effectiveness for aspirin and acetaminophen. The doctor has $600\text{ volunteers}$ for this study.

The doctor randomly selects $200$ of these volunteer subjects receive aspirin, $200$ to receive acetaminophen and the remaining $200$ to receive a placebo pill.

Which of the following statements is correct?

A

The sample size should be larger for an experiment such as this one.

B

A placebo, in this case, is not necessary.

C

A matched pairs design should have been used in this case instead of the process described.

D

The doctor should have let the subjects choose which group they want to be in so that the subjects feel more comfortable.

E

This experiment should be conducted in a double-blind manner.

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