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Serum glycoproteins play many roles in an organism, but they eventually need to be removed from circulation.

Newly-synthesized glycoproteins all contain oligosaccharide chains that end with
Select Option an adenyl groupa methyl groupsialic acidubiqutin
. Glycoproteins that have grown too old lose that tag, and are recognized by the
Select Option asialoglycoproteinglycoprotein IIb/IIIa (integrin ${\alpha}_{II}{\beta}_{3}$)insulinretinoid X
receptor in the
Select Option kidneyliverpancreasspleen
. Upon binding, the glycoproteins are then internalized and destroyed.
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