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Erythropoietin is a glycoprotein hormone that stimulates the production of red blood cells from progenitor cells in the bone marrow.

The organ that releases erythropoietin is the
Select Option heartkidneybrain
. When oxygen levels drop, erythropoietin is released and travels to the bone marrow.
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Erythropoietin receptors belong to the
Select Option cytokineG-protein coupledtyrosine kinase
family of receptors and are located on
Select Option erythroidglialmyocyte
precursor cells. The receptors preexist in a
Select Option single pass transmembrane homodimerizedheterodimerized
state which demonstrates a conformational change upon stimulation by erythropoietin. The conformational changes result in
Select Option transphosphorylationtranslocationautophosphorylation
of preassociated JAK2 kinases.
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Erythropoietin promotes
Select Option autophagyproliferationshrinkage
and rescue of erythroid (red blood cell) progenitors from
Select Option killer B lymphocytesapoptosisosteoclasts
.
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