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Receptor protein-tyrosine kinases (RTKs) are transmembrane proteins that contain an extracellular ligand-binding domain outside a cell and an intracellular domain within the cytoplasm that can activate downstream signaling pathways by phosphorylation.

What is true about RTK phosphorylation?

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RTKs are active as dimers.


'Phosphorylation​' denotes the act of an enzyme catalyzing the transfer of phosphate groups.


RTKs act on a specific signalling protein.


The phosphate group transferred by the kinases come from elemental phosphate within the cytosol.

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