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Movement through cell cycle checkpoints is dependent on the relationship between cyclin proteins and cyclin-dependent kinases (CDKs).

Which of the following, regarding progression through a cell cycle checkpoint, are CORRECT? Select ALL that apply.

A

Cyclin concentrations remain constant throughout the cell cycle.

B

Cyclin concentrations fluctuate throughout the cell cycle.

C

CDK concentrations fluctuate throughout the cell cycle.

D

CDK concentrations remain constant throughout the cell cycle.

E

CDKs phosphorylate proteins to activate them, allowing progression through the cell cycle.

F

Cyclins phosphorylate proteins to activate them, allowing progression through the cell cycle.

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