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Cleavage is the first stage of embryonic development, occurring immediately after the egg and sperm fuse to form a zygote.

Which of the following developmental milestones occurs during cleavage in mammals? Select ALL that apply.

A

The embryo becomes multicellular.

B

The embryo’s size increases substantially.

C

The embryo develops limb buds.

D

The embryo is organized into future developmental regions.

E

The embryo forms a fluid-filled cavity at its center.

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