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A cell's energy requirements vary depending on its current needs. That means in times of low energy needs, the Krebs cycle should be slowed down. In times of high energy needs, the Krebs cycle should be sped up. To help respond to different times such as these, there are several key regulation points in the Krebs cycle.

Which enzymes are part of key regulation points in the Krebs cycle (hint: they all have a large $ -\Delta G$)?

Select ALL that apply.

A

Citrate synthase.

B

Isocitrate dehydrogenase.

C

$\alpha$-ketoglutarate dehydrogenase complex.

D

Succinate dehydrogenase.

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