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Upon DNA damage, the nuclear BRCA1 protein is involved in repairing double-stranded breaks in DNA through its interaction with other proteins, forming a multi-protein complex that facilitates the process of homologous recombination. However, when the BRCA1 gene is mutated, the resulting BRCA1 protein can no longer serve its function, and cancer may develop as a result.

Which of the following BEST describes the role of the wild-type BRCA1 gene in cell cycle control?

A

The BRCA1 gene is a proto-oncogene.

B

The BRCA1 gene encodes a growth factor.

C

The BRCA1 gene is an oncogene.

D

The BRCA1 gene encodes a cyclin protein.

E

The BRCA1 gene encodes a tumor suppressor protein.

F

The BRCA1 gene encodes a cyclin-dependent kinase.

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