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Genomic sequencing of human bacterial pathogens may be used to predict and/or prevent outbreaks by such pathogens. Scientists are now able to complete sequences that have published gaps using next-generation sequencing, which involves the steps shown here.

The fragments that are produced must be compared and aligned using overlapping segments known as

Genomic DNA is fragmented into random pieces and cloned as a bacterial library. DNA from individual bacterial clones is sequenced and the sequence is assembled.. By Abizar at English Wikipedia, Public Domain,


contiguous DNA sequences.


complementary DNA sequences.


reference DNA sequences.


wild-type DNA sequences.

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