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Consider a single locus (the A locus) with two alleles (A1 and A2) in a population. The parents (male and female averaged together) have 0.5 frequency of the A1 allele and 0.5 frequency of the A2 allele.

The frequency of heterozygotes in the progeny generation under Hardy-Weinberg expectations (random mating, no selection, no drift, no mutation) is
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; however, the maximum frequency of heterozygotes possible in the progeny generation when artificial selection (parents are chosen by a person) is imposed is
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