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Intragenic suppression is when a second mutation in a gene restores the function of the gene disrupted by a previous mutation.

Which of the following is LEAST likely to result in intragenic suppression?

A

A single base pair deletion (first) suppressed by a single base pair insertion (second).

B

A single base pair deletion (first) suppressed​ by a two base pair deletion (second).

C

A missense mutation (first) suppressed​ by a second missense mutation (second).

D

A two base pair deletion (first) suppressed by a single base pair insertion (second).

E

A two base pair insertion (first) suppressed​ by a single base pair insertion (second).

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