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As chromosomes are very large molecules, they must be packaged by eukaryotic cells in order to allow them to function within the nucleus.

Which of the following statements is TRUE about eukaryotic chromosome packaging?

A

Phosphate groups cause DNA to have a positive charge that allows them to wrap around negatively charged histone proteins.

B

Specialized proteins bind and fold the DNA, forming loops and coils to organize the DNA and prevent it from becoming tangled and unmanageable.

C

Eukaryotic chromosomes are packaged to form an "X" shape throughout the cell cycle.

D

Chromatin is the packaged DNA complexed with ribosomal RNA via ionic bonds.

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