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Restriction endonucleases originate from bacteria and are easy to use and extremely useful in biotechnology, especially if the fragments they produce contain “sticky” or “staggered” ends.
What makes these DNA fragments “sticky?”
They stay together and pile on top of each other.
Their ends are blunt.
Their ends can attack viral DNA and digest it.
These staggered ends can only bind exclusively to ends of DNA belonging to different organisms.
They have single-stranded complementary tails.