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Below is a pedigree showing inheritance of a rare autosomal recessive disorder in a family. Each of the members of the family had RFLP analysis done using a DNA probe from a region of the mutant gene in question. The Southern blotting was performed using their genomic DNA digested with the enzyme Hind III. Individual 5 is expecting her first child with a man whose father has this rare autosomal recessive disease. They are concerned about the health of the child.

Mary Ellard-Ivey. Created for Albert.io. Copyright 2017. All rights reserved.

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