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A virus has infected some cells through an open wound. Viral proteins are now being presented on all the HLA Class I molecules shown below.

MHC class I molecules expressed by four individuals infected with a virus. Individual 1 expresses HLA A1 and A2. Individual 2 expresses HLA A3 and A2. Individual 3 expresses HLA A3 and A1. Individual 4 expresses HLA A3 only. Created for Copyright 2016. All rights reserved.

The virus quickly mutates its epitope that binds HLA-A3, so that it no longer binds any peptides.

Assuming that the individuals above only have 2 MHC Class I molecules, which individual(s) is(are) at risk of dying from infection?


Individuals 2, 3, and 4.


Individual 4.


Individual 3.


Individual 2.


Individual 1.

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