Limited access

Upgrade to access all content for this subject

The interactions between germinal center B cells and T$_{FH}$ CD4$^+$ T cells are essential for class switching of the heavy chains of antibodies to a different isotype. The antibody isotype ultimately determines the effector function of the antibody.

Besides cytokines released during T cell help, what other molecule determines the choice of isotype that is selected?

A

CTLA-4

B

CD40 ligand.

C

MHC Class II.

D

CD80.

E

CD86.

Select an assignment template