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Two distinct lineages of T cells can be identified based on their expression of $\alpha$:$\beta$ versus $\gamma$:$\delta$ T-cell receptors.

A deficiency in the signaling receptor Notch1 would result in

A

a loss of $\alpha$:$\beta$ but not $\gamma$:$\delta$ T cells

B

a normal number of both of $\alpha$:$\beta$ and $\gamma$:$\delta$ T cells

C

a loss of $\alpha$:$\beta$ T cells and a massive expansion of $\gamma$:$\delta$ T cells

D

an increased number of both of $\alpha$:$\beta$ and $\gamma$:$\delta$ T cells

E

a loss of both of $\alpha$:$\beta$ and $\gamma$:$\delta$ T cells

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