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The earliest known reference to the phenomenon of immunity is from the Ancient Greek historian Thucydides, who wrote about the Peloponnesian War between Athens and Sparta during the years 430-411 BC. During an outbreak of the plague, he noticed that those who had recovered from the plague could attend to the sick because they would not contract the disease a second time.

If the Latin term immunis means ‘exempt from,’ then which choice below is the BEST definition of immunity?


The state of having been exposed to the plague.


An individual has never been exposed to the plague.


The state of being resistant to reinfection with the plague.


The state of being resistant to infection with the plague.

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